[Literature library] Factors influencing maternal vitamin D levels in China

Overall status of serum vitamin D levels:

• The median serum 25-(OH) D level of all pregnant women was 33.7 (24.7, 44.7) nmol/L
• Deficiency rate: 83.28% [25-(OH) D < 50 nmol/L]
• Insufficiency rate: 15.36% [50 nmol/L ≤ 25-(OH) D < 75 nmol/L]
• Sufficiency rate: 1.36% [25-(OH) D ≥ 75 nmol/L]
   

Protective factors for vitamin D sufficiency:

• Gestational age between 28 and 32 weeks
• Summer and autumn
• High school education and above
• Weekly time outdoors ≥ 10 hours
• Supplement of vitamin D and trace elements during pregnancy
   

Influence of air temperature:

• Maternal serum vitamin D level was highly positively correlated with air temperature
   

Common adverse pregnancy outcomes:

• Maternal vitamin D level was associated with incidence of spontaneous abortion and small-for-gestational age (SGA)
  • The incidence of spontaneous abortion in ‘vitamin D deficiency group’ was the highest, with 402 cases out of 421 total cases  
  • The incidence of SGA in ‘vitamin D deficiency group’ was the highest, with 410 cases out of 423 total cases
     

Link to the full article:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8519205/pdf/medi-100-e27505.pdf
 

Reference:

Chen B et al. Vitamin D deficiency in pregnant women: Influenced by multiple risk factors and increase the risks of spontaneous abortion and small-for-gestational age. Medicine (Baltimore). 2021;100(41): e27505.
 

Other articles that you might be interested in:

Vitamin D in Paediatric Nutrition
 

WYE-EM-215-DEC-21