Human Milk Oligosaccharides (HMO)
Importance of faecal biomarkers and the microbiome’s role in child health and disease… Is it really all about the poop? - Dr. Ben Gold
Diet, environment and microbiota in infancy are factors that can support gut barrier function and immune development. Studies show that nutrition interventions, particularly breastfeeding and human milk oligosaccharides, may influence the development of a normal microbiome.
[Hot science] Two types of HMOs, infant fecal community types and antibiotic uses
Following a previous report demonstrating the safety and tolerance of an infant formula containing two major types of HMOs (2’-fucosyllactose and lacto-N-neotetraose), the authors further assessed the impact of HMO-supplementation on infant fecal community type as well as its relationship with re
[Literature Library] Review on the role of two human milk oligosaccharide, 2’-fucosyllactose and lacto-N-neotetraose, in infant nutrition
This review provided insight into human milk oligosaccharides (HMOs), the third abundant component of human milk. It summarized current evidence and concluded functions and health benefits of HMOs.
Carbohydrates in human milk and body composition of infants during the first year of life
This study investigated relationships between the intake of human milk carbohydrates in the first year of life and infant body composition. Higher total carbohydrate concentrations, including human milk oligosaccharides (HMOs), were associated with increased lean mass and reduced adiposity.
[Literature Library] Bovine milk oligosaccharides (BMOs) influence growth-related characteristics of intestinal cells
This in vitro study found that specific BMOs could inhibit intestinal cell proliferation and have effects on gut differential processes, indicating BMOs may play a role in gastrointetinal development and maturation.
[Literature Library] Structures and metabolic properties of bovine milk oligosaccharides (BMOs)
This review detailed the potential metabolic effects of bovine milk oligosaccharides (BMOs) that may be structurally similar to human milk oligosaccharides (HMOs) and explored the possibility of their industrial production for therapeutic uses.
[Literature Library] Antibacterial properties of human milk oligosaccharides (HMOs)
The authors have identified several HMOs with potent antimicrobial activity against the pathogen Group B Steptococcus, and uncovered the mechanism of action of HMO antimicrobial activity such as by increasing bacterial cell permeability.