961 elderly female patients over the age of 70 years were recruited from nursing homes in Austria and the serum level of 25-hydroxy vitamin D [25(OH)D] was measured in February and March.
- Key findings:
- Median 25(OH)D concentration was 17.5 nmol/L and 93% had 25(OH)D levels below 50 nmol/L (recommended level).
- 284 patients died during a mean follow-up time of 27 ± 8 months.
- When adjusted for age, those with 25(OH)D lower than 14 nmol/L had 1.49 increased risk of mortality compared to those with 25(OH)D higher than 25.5 nmol/L.
The majority of institutionalized female patients are vitamin D deficient during winter, and 25(OH)D level is inversely associated with mortality.
Pilz S, Dobnig H, Tomaschitz A, Kienreich K, Meinitzer A, Friedl C, Wagner D, Piswanger-Sölkner C, März W, Fahrleitner-Pammer A. Low 25-Hydroxyvitamin D Is Associated with Increased Mortality in Female Nursing Home Residents. J Clin Endocrinol Metab. 2012 Feb 8. [Epub ahead of print]. Link to PubMed