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Growth and morbidity of infants are influenced by maternal milk oligosaccharides and infant gut microbiota

Growth and morbidity of infants are influenced by maternal milk oligosaccharides and infant gut microbiota

Study findings showed longitudinal changes in human milk oligosaccharide (HMO) composition in human milk, as well as shifts in the infant’s gut microbiota were both associated with infant health outcomes. Specific HMOs may potentially lead to protection with lower rates of infection and/or inflammation, allowing the infant to invest energy in growth.

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These results suggest that specific types and structures of HMOs are sensitive to environmental conditions, protective of morbidity, predictive of growth, and correlated with specific microbiota.

Reference

Davis J, et al. Growth and morbidity of Gambian infants are influenced by maternal milk oligosaccharides and infant gut microbiota. Sci Rep. 2017; 40466.