The Synergy between Lactose and Bovine Milk Oligosaccharides (BMOs)


This study compared the prebiotic effect of bovine milk oligosaccharides (BMO) and synthetic galacto-oligosaccharides (GOS) using mono- and cocultures of eight major bacteria related to a healthy infant microbiome. The results revealed that BMO treatments supports growth of B. longum subsp. longum. In addition, there was found a synergistic effect of combining lactose and BMO in regard to reducing Clostridium perfringens, maintaining stable numbers of Parabacteroides distasonis and simultaneously increasing numbers of the beneficial B. longum subsp. logum.

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Jakobsen LMA et al. Lactose and bovine milk oligosaccharides synergistically stimulate B. longum subsp. longum growth in a simplified model of the infant gut microbiome. J Proteome Res. 2019;18(8):3086-3098.

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